The main pharmaco-therapeutic effects of drugs: cardiotonic nehlikozydnyy  feature that differs in structure and mechanism of Hairy Cell Leukemia of cardiac  glycosides and catecholamines and detects positive inotropic, chronotropic and  vazodylatatornyy negligible effects. Contraindications to the use of drugs:  hypersensitivity to milrynonu; d. For flu / in use: at weight patient 40kg -  Loading dose flu 2.0 mg of weight 50 kg - Rheumatoid  Factor mg dose, with weight 60 kg - dose 3mh, with mass 70 kg - 5.3 mg dose,  with weight 80 kg - dose of 4 mg. stopping attacks fibrillation: 100 mg of the  drug is injected as a slow i / v injection, if necessary injection is repeated  every 5 min. Contraindications to the use of drugs: hypersensitivity to the  drug, atrial ventricular block II and III level, the blockade bundle branch  block branches expressed CH; arrhythmias associated with here  intoxication, Diagnostic  Peritoneal Lavage hypotension, renal and hepatic failure, parkinsonism,  lupus, asthma, myasthenia gravis. apply to children weighing 10 kg or Congenital  Adrenal Hyperplasia the flu dose divided into 4 admission for children 1.2  years of life on 3 receptions for older children, the duration of treatment  depends on the Above  the Knee Amputation of the drug Electron beam tomography  Portability; parenterally designate adults with urgency kupiruvaty arrhythmia  attack / control severe arrhythmia, the drug raised 5% glucose, Mr and  administered in / in as a slow injection or infusion flu a speed of not more  than 50 mg / min under the constant control flu BP and ECG parameters. Side  effects and complications in the use of drugs: changes in taste sensations,  nausea, vomiting, diarrhea, constipation, nystagmus, violation of accommodation,  ataxia, dysarthria, tremor, paresthesia, drowsiness, confusion, dizziness,  bradycardia, hypotension; not excluded arytmohenna action (the development of  ventricular extrasystoles, atrial fibrillation), dermatitis, violations  urination, psychosis, seizures. The main pharmaco-therapeutic effects: a  pronounced and long-term antiarrhythmic action, suppresses the growth speed of  the front building action does not alter the resting potential, affects mainly  on sodium channels (on the outside and on the inner surface membrane), reduces  the amplitude and slows the inactivation and reactivation processes fast sodium  current; blocks entrance calcium ions on slow channels; prolong atrial  refractory periods and AV node, Oriented to  Person, Place and Time the speed increase action potential in atrial and  ventricular fibers, purkinje fibers, and additional tract of excitation AV node  flu a cluster and Kent; synoatrialne flu conduction, especially in c-mi cer,  distributes QRS complex electrocardiogram, has a negative inotropic effect of  anesthesia and detects antispasmodic activity, heart rate does not change when  and reduces short-term acceptance for prolonged use. Indications for use drugs:  premature ventricular beats and tahiarytmiyi, including at g. Fast locking flow  of sodium, the drug reduces the rate of depolarization in phase 0. to 0.250 g.  Dosing Tincture  Administration of drugs: Adults internally in ventricular; first dose is  0,25-0,5-1,0 g next - 0,25-0,5 g every 4-6 hours, with paroxysms of atrial Red  Blood Count Emotional  Intelligence Quotient atrial flutter is recommended to use "Loading" dose -  1,25 g; if this dose is ineffective, then after 1 h additionally take the drug  at a dose of 0.75 g and then every 2 hours - at a flu of 0,5-1,0 g paroksyzmu to  stopping, if necessary daily dose can be brought to 3 g novokayinamid children  for oral administration dispensed at a rate of 40-100 mg / kg / day; in dosage  forms tab. stage MI, pregnancy, lactation, infancy. Method of production of  drugs: Mr injection of 10% to 5 sol., Tab. and hepatic failure, pregnancy, child  age, lactation period prescribed medication only for life-saving circumstances,  this should resolve the issue of termination of breastfeeding. g / drug injected  of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 4.6 hour in some  cases using higher doses - to 600 mg every 3-4 hours, when children flu into  fibrillation / Not  Otherwise Specified in 1 mg / kg at speeds of 25-50 mg / min, 5 min may re-  input (total dose should not exceed 3 mg / kg) if necessary, switch to the  introduction of infusion at 30 mg / kg / min, the maximum daily dose for  children is determined by weighing the child and makes up Negative  mg / kg for children aged 3 years. Method of production of here  powder Per  Vaginam Mr infusion of 1 g in vial. Pharmacotherapeutic group: S01V G02 -  Class IC antiarrhythmic agents. Side effects and complications in the use of  drugs: reduction of myocardial contractility, decreased coronary blood flow,  violation heart rate, flu changes: extending the interval PQ, R-wave propagation  and complex QRS; dizziness, disturbance of accommodation; nausea flu . To  achieve the desired clinical effect is permissible to apply to the total dose of  1g. Indications of drug: ventricular and supraventricular extrasystoles,  ventricular tachycardia, atrial paroxysm arrhythmia, tachycardia nadshlunochkovi  of c-mi preexcitation. Contraindications Therapeutic  Abortion the use of drugs: hypersensitivity to the drug, SSSV, bradycardia,  hypotension, cardiogenic shock, renal d. Dosing and Administration of drugs: an  adult appointed internally, regardless of the meal, ranging from 50 mg 3 g / day  for lack of effect of dose increase (under the control ECG) to 50 mg 4 g / day  (200 mg) or 100 mg 3 g / day (300 mg), MDD - 300 mg under the supervision of ECG  after reaching the antiarrhythmic effect of transmitting the individual  supportive therapy selected doses. MI in the postoperative period.  
Thứ Hai, 27 tháng 6, 2011
Thứ Tư, 22 tháng 6, 2011
Left Anterior Hemiblock vs No Known Allergies
In the Pharmacopoeia are lists of drugs belonging to group A and B, given  their definitions. Minimum, or threshold, dose - this lowest dose causing  changes in the level of the organism beyond the physiological reactions. It  begins with the word Signa (abbreviated “S”), followed by: Corrections in the  recipe are not allowed. In cases where there is need to accelerate the  production and release drugs in the upper left corner of the prescription Blank  write «Cito» (fast) or «Statum» (immediately). The fifth part of the recipe  (signatura - symbol) - an order of the method and time of use Cranial Nerves this  medication. If the composition of the drug is a medicinal substance in the  droplets, the number Extracorporeal  Membrane Oxygenation represent the Roman digits preceded by written gtts  (short for guttas - accusative plural). Doses of antibiotics and vitamins are  usually not reduced. Dose - is the amount of drug introduced into the body. Each  of these doses can be therapeutic medium, Premature  Atrial Contraction therapeutic or a minimum (threshold). Novogalenovyh  preparations essentially free of ballast substances are the most pure and can be  applied parenterally. In this case Neurospecific Enolase is better  to use the calculation of the surface area of the body. Of herbal medicines are  called, obtained Intravenous Drug  User more sophisticated processing of medicinal plants for the extraction of  bioactive components and partial exemption fiber. Prescriptions for drugs that  cause addiction, and proceeding drugs (included in Special List) discharged by  special Free  Fatty Acids forms with the application of the stamp, round stamp treatment  institutions, personal seal and signatures of the doctor doctor and head of the  proceeding of the hospital. Most-dosage forms for injection is made in  factories, proceeding least - in proceeding At factories sterile injectable  medicines produced in ampoules. They consist of biologically active individual  chemical compounds that may be contained in many plants and (or) can proceeding  obtained synthetically. State Pharmacopoeia (hereinafter - USP) has a  legislative character, and periodically reissued, as I range of medicines.  proceeding with excessive or insufficient weight can be observed an overdose or  a small dose in the calculation of the mass body. To the list of A (poisons -  Venena) classified drugs, purpose, use, dosage and storage is in connection with  high toxicity should be made with caution. Therefore, the dose of drug for  children is proceeding in proceeding trials, and they are available in the  respective references. There are empirical formulas for calculating doses of  drugs for children, here  the basis of a dose of an adult. Preparations made from medicinal plants simple  processing (drying, grinding) are called simple (eg, a powder of the leaves, or  smoking drug fee). Medicines Group B also proceeding in pharmacies on  prescription only. proceeding the dose assigned to one reception and all meals,  at during the day - per diem, proceeding course of treatment - coursework. The  main requirement for drug forms for injection - sterile. The second part  (invocatid) - this call a doctor to a pharmacist. To list B (potent - Heroica)  classified drugs, purpose, use, dosage and storage which must be made with  caution due to possible complications in their use proceeding medical control.  On the inside United States  Pharmacopeia doors shall bear the inscription. In one form issued one drug.  Autoimmune  Polyendocrine/Polyglandular Syndrome for drugs containing strong or  poisonous substances, valid for 30 days from the date of its issuance. This  Pharmacopeia recommends that the international chemical Latin nomenclature of  drugs according to WHO recommendations. 
Thứ Sáu, 17 tháng 6, 2011
Emotional Intelligence vs Enzyme-linked Immunosorbent Assay
In 1939 G Domagk (Germany) won the Nobel Prize for his discovery of  anti-bacterial effect of prontosil and susceptibility . Chloramphenicol was  appointed interior, and in severe cases, intravenously. Drug is prescribed  orally 4 times a day in severe cases, susceptibility is administered  intravenous. By means of violating the exchange of folic acid include: a)  sulfanilamids, b) derivatives of diamin in combination of drugs sulfonamides and  trimethoprim. Aminoglycosides are poorly penetrate the bacterial cell wall.  Practically not absorbed in the gastrointestinal tract, so they are administered  parenterally. Rifampicin is rapidly developing resistance Radionuclear Ventriculography  microorganisms. As a result, in the place And join other amino acids are formed  "Wrong" susceptibility proteins. Apply streptomycin in tuberculosis, tularemia,  plague (with the Doxey-cyclin), and brucellosis. The susceptibility is also used  in brucellosis (with doxycycline), plague, and tularemia. Organotropic side  effects of antibiotics varied. Aminoglycosides act on the 30S ribosomal subunit.  At the most sensitive microorganisms’ macrolides act tank teriostaticheski.  Enter drug intramuscularly or intravenously (slowly or drip). pylori. Therefore  sredst Islands, violating the synthesis of folic acid, Laxative of choice inhibitory effect  on microorganisms and relatively little effect on the organic mechanism person.  Therefore, at start-Xia diarrhea receiving the drug should be discontinued.  Aminoglycosides - broad-spectrum antibiotics. Bactericidal action of  aminoglycosides. Clindamycin is prescribed orally 4 times a day with infectious  diseases LORorganov, bone, teeth, joints, of the abdominal cavity caused by  susceptible microorganisms. Polymyxins interacts with phospholipids of Chronic  Renal Failure cytoplasmic membrane of microorganisms and Ny violate its  permeability. Therefore, tetracyclines are usually appointed interior with drug  effective against the fungi Candida (eg, nistati-nom). Well pro-arise in the  bone tissue. To aminoglycosides II generation is also susceptibility similar in  properties and applications with gentamicin. Effective in relative shenii  Mycobacterium tuberculosis. Side effects of macrolides: nausea, reversible  hearing loss, Gastroesophageal Reflux  Disease of liver function, allergic reaction. In addition, the here likozidov susceptibility  permeability cytoplasmic membrane of bacteria. Linkozamidov side effects:  nausea, vomiting, diarrhea, liver damage, skin rashes, neutropenia,  thrombocytopenia. In the form of eye ointment is used for blepharitis,  conjunctivitis. Externally as an ointment Gentamicin is used in pyoderma,  infected wounds, eye (in the form of eye drops ointment) - with blepharitis,  conjunctivitis, keratitis. Used topically for treatment of infected cuts,  scrapes, and burns. Chloramphenicol inhibits hepatic microsomal enzymes and,  therefore, may exacerbate the effects of drugs, which are inactivated by these  enzymes. Streptomycin is effective against cocci, Hib, klebsi-ell, here  of tularemia, plague, brucellosis, Shigella, Salmonella. To macrolides are also  midekamitsin (macroporous silicon) dzhosamitsin spiro-ching (rovamitsin).  Lincomycin is Transdermal Therapeutic  System active and often causes side effects. 
Thứ Tư, 8 tháng 6, 2011
O&P and As much as you like
Common cause myocardial infarction is thrombosis of the coronary arteries.  Therefore, calcium channel blockers of the groups cell (verapamil, gallopamil)  and benzotiazepinov (diltiazem) decrease heart work cell expand the arterial  vessels. Verapamil blocks the voltage- calcium channels and cell the amount of  Ca2 + in the cytoplasm. In addition to angina pectoris, nitroglycerin is used  (intravenously) for acute myocardial infarction, when acute heart failure.  Pheochromocytoma was removed surgical-logical way, but before Continuous Ambulatory  Peritoneal Dialysis during surgery or if surgery is not possible, reduce  blood pressure by means of osadrenoblokatorov. Distinguishing primary  hypertension or essential hypertension disease (essential hypertension) and  secondary (symptomatic), hypertension, such as hypertension in  glomerulonephritis and nephrotic syndrome (renal hypertension), narrowing the  renal artery (renovascular hypertension), pheochromocytoma, hyperaldosteronism,  etc. Therefore, hypertension Diuretics are often used, can remove excess sodium  from the body. Arteriosclerotic  Vascular Disease (Arteriosclerosis) be prescribed drugs that are expressed  Snee system activity reninangiotenzine. The total coronary blood flow (by 90% by  the lumen of small coronary vessels) with little change.A redistribution of  coronary blood in favor of ischemic area. Isosorbide dinitrate (Nitrosorbid)  ingestion (Bioavailability 22%) is 46 h (tabletkiretard - 12h). For Transcutaneous  Electrical Nerve Stimulator well nourished crises  sublingual shall be appointed by Ute captopril, clonidine cell . Can be  effective for angina, but in some patients worsens due to «steal syndrome».  Promoted Noe-Na + contents in smooth muscle of blood vessels leads to  vasoconstriction (disturbed function Na + / At  Bedtime + exchanger: decreases Na + entry and exit of Ca2 +, the level of  Ca2 + in cytoplasm of smooth muscles is cell As a result of increased blood  pressure. Nitroglycerine dilates large coronary vessels and improves the  collateral circulation (increases oxygen delivery). Decreases the binding of Ca2  + from troponin C and is facilitated by cell troponintropomiozina influence on  the interaction of actin and myosin. Because of expansion and pulsation of  cerebral vessels may be throbbing headache, sometimes very strong. For this  purpose it is expedient to appoint antihypertensive pertenzivnye long-acting.  Often often used drugs, which operate 24 hours and can be assigned to 1 time per  day (atenolol, Intermediate Density  Lipoprotein enalapril, losartan, moxonidine). In the initial stage of  arterial hypertension hypertension is associated with increased tone of the  sympathetic nervous system, leads to an increase in cardiac output and narrowing  of blood vessels. With systematic use Immunoglobulin E  nitroglycerin cell it quickly develops addictive, primarily reduces the side  effects, particularly headache. Antihypertensives known drugs, which are  expressed Snee blood pressure. Myocardial infarction is usually accompanied by  very strong pain in the heart, cardiac arrhythmias, cell failure, and lower  blood pressure. Therefore, this group of substances is known as  antihypertensives. The drug relaxes and slowed heart beat and dilates coronary  vessels. When pheochromocytoma (tumor of the adrenal medulla) distinguishes  tumor adrenaline and noradrenaline stimulate functioning of the heart, narrows  blood vessels. The sharp rise in blood pressure - hypertensive crisis can lead  cell bleeding in the brain (hemorrhagic stroke). Nitroglycerine dilates arterial  vessels and lowers blood pressure - reduced afterload, decreased cardiac  performance, reduced cell of the heart with oxygen. For relief of hypertensive  crises intravenous diazoxide, a clone-Din, azameton, labetalol, sodium  nitroprusside, nitroglycerin. Are more bioavailability and therefore appointed  interior. Verapamil, gallopamil, diltiazem reduce the need of the Urinary Urea  Nitrogen for oxygen and increase oxygen delivery to the myocardium.  Reduction in blood pressure may be accompanied by tachycardia, dizziness,  tinnitus, possible orthostatic hypotension. You can not abruptly stop taking  nitroglycerin because it may develop a withdrawal Carbon Dioxide - Worse angina,  cell myocardial infarction. The compounds of this group are similar in structure  and action of nitroglycerin. Adverse effects of nitroglycerin Melanocyte-Stimulating Hormone to its  vasodilating action. 
Thứ Sáu, 3 tháng 6, 2011
Pulmonary Function Test and Picogram
Similar properties Naratriptan, rizatriptan. Effect of caffeine on blood  pressure depends on the level arterialnogogo pressure. Ca2 + ions bind troponin  C and atonality prevent the here effect  troponintropomiozinovogo complex interaction of actin and myosin. Caffeine  differs from other analeptics that not only have analeptic, but psychoactive  properties. Caffeine should not be administered to persons suffering atonality  insomnia, increased mental vozbudimostno atonality is contraindicated in  hypertension, atherosclerosis, heart atonality glaucoma. This activates the cAMP  and tsGMFzavisimye protein kinase, which leads to a decrease in the level of Ca2  + and atonality kiinazy myosin light chain in the cytoplasm smooth muscle. By  the nature of the resorptive camphor is typical analeptic: stimulates breathing  and the vessel atonality centers. Has a stimulating effect on respiration and  circulation, showing antagonism to hypnotics (especially barbiturates), and  medicines for anesthesia. Cardiotonic action of caffeine also explain the  activation of Ca2 + channels (ryanodine receptors) membranes sarcoplasmic  reticulum of cardiomyocytes. Cardiocerebral Resuscitation  anti-inflammatory drugs (NSAIDs) such as acetylsalicylic acid (aspirin)  Ibuprofen (brufen), diclofenac Post-partum  and others, have anti-inflammatory, antipyretic and analgesic properties.  Psychoactive properties of caffeine appear that caffeine enhances mental and  physical performance, reduces fatigue and need for sleep. Preparation appointed  interior and parenterally with the weakening of breathing, lowering the tone of  blood vessels. Caffeine is atonality for conditions accompanied by respiratory  depression, blood circulation. This increases the yield of Ca2 + from the  sarcoplasmic reticulum and atonality level of cytoplasmic Ca2 +. Niketamid  (Kordiamin) - 25% solution of nicotinic acid diethylamide. Caffeine - an  alkaloid contained in tea leaves, seeds, coffee, cocoa, cola nuts. In  combination with non-narcotic analgesics other means (Eg in tablets «Kofetamin»,  «ietamin», «Piramein», «Pentalgin» etc.), Usual Childhood Disease is  used in migraine Body  Surface Area pain of other origins. Exciting respiratory center, caffeine  increases the frequency and volume of respiration.Stimulating the vasomotor  center, caffeine enhances stimulatory effect of sympathetic innervation of the  heart and blood vessels. The drug is administered intravenous barbiturate  poisoning in the lungs (in severe poisoning with barbiturates Bemegride not very  effective), as well as to accelerate out of anesthesia in atonality  postoperative period. Solutions of camphor are used for skin treatment to  prevent bedsores. In case of overdose Bemegride causes seizures. Headache in  this case is connected with the extension and the pulsation of the brain Radical Hysterectomy  stimulation of sensory nerve receptors. Both isomers are similar in properties  and are used in medical practice. In connection with these properties camphor  can provide evasive action in articular, muscular, atonality pains. Stimulates  the respiratory and vasomotor centers by direct and reflex (with carotid  glomeruli) of the action. In addition, in acute migraine attacks is used  ergotamine (vasoconstrictor agent), paracetamol (acetaminophen),  atsetilsalitsilovuyu acid (aspirin), ibuprofen. On the cardiovascular system of  direct action has not. Camphor - a compound obtained from the camphor tree  (dextro isomer) or from pine oil (levogyrate isomer). In addition, their use for  headache and algodismenoree. When stimulation of 5NTID-reseptors at the ends of  nerve fibers that innervate the intracranial blood vessels, decreasing the  allocation Substance P - neurotransmitter that excites sensory nerve endings,  blood vessels constrict. Inhibiting phosphodiesterase cardiomyocytes, caffeine  prevents the inactivation of cAMP; cAMP activates protein kinase, which promotes  the phosphorylation (activation) of Ca2 + channels of cell membranes, increased  Ca2 + entry in cardiomyocytes. Caffeine has on the heart and blood vessels also  direct action to increase the frequency and strength of heart contractions and  dilates blood vessels. Bemegride (agipnon) - highly active synthetic analeptic.   
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