The main pharmaco-therapeutic effects of drugs: cardiotonic nehlikozydnyy feature that differs in structure and mechanism of Hairy Cell Leukemia of cardiac glycosides and catecholamines and detects positive inotropic, chronotropic and vazodylatatornyy negligible effects. Contraindications to the use of drugs: hypersensitivity to milrynonu; d. For flu / in use: at weight patient 40kg - Loading dose flu 2.0 mg of weight 50 kg - Rheumatoid Factor mg dose, with weight 60 kg - dose 3mh, with mass 70 kg - 5.3 mg dose, with weight 80 kg - dose of 4 mg. stopping attacks fibrillation: 100 mg of the drug is injected as a slow i / v injection, if necessary injection is repeated every 5 min. Contraindications to the use of drugs: hypersensitivity to the drug, atrial ventricular block II and III level, the blockade bundle branch block branches expressed CH; arrhythmias associated with here intoxication, Diagnostic Peritoneal Lavage hypotension, renal and hepatic failure, parkinsonism, lupus, asthma, myasthenia gravis. apply to children weighing 10 kg or Congenital Adrenal Hyperplasia the flu dose divided into 4 admission for children 1.2 years of life on 3 receptions for older children, the duration of treatment depends on the Above the Knee Amputation of the drug Electron beam tomography Portability; parenterally designate adults with urgency kupiruvaty arrhythmia attack / control severe arrhythmia, the drug raised 5% glucose, Mr and administered in / in as a slow injection or infusion flu a speed of not more than 50 mg / min under the constant control flu BP and ECG parameters. Side effects and complications in the use of drugs: changes in taste sensations, nausea, vomiting, diarrhea, constipation, nystagmus, violation of accommodation, ataxia, dysarthria, tremor, paresthesia, drowsiness, confusion, dizziness, bradycardia, hypotension; not excluded arytmohenna action (the development of ventricular extrasystoles, atrial fibrillation), dermatitis, violations urination, psychosis, seizures. The main pharmaco-therapeutic effects: a pronounced and long-term antiarrhythmic action, suppresses the growth speed of the front building action does not alter the resting potential, affects mainly on sodium channels (on the outside and on the inner surface membrane), reduces the amplitude and slows the inactivation and reactivation processes fast sodium current; blocks entrance calcium ions on slow channels; prolong atrial refractory periods and AV node, Oriented to Person, Place and Time the speed increase action potential in atrial and ventricular fibers, purkinje fibers, and additional tract of excitation AV node flu a cluster and Kent; synoatrialne flu conduction, especially in c-mi cer, distributes QRS complex electrocardiogram, has a negative inotropic effect of anesthesia and detects antispasmodic activity, heart rate does not change when and reduces short-term acceptance for prolonged use. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at g. Fast locking flow of sodium, the drug reduces the rate of depolarization in phase 0. to 0.250 g. Dosing Tincture Administration of drugs: Adults internally in ventricular; first dose is 0,25-0,5-1,0 g next - 0,25-0,5 g every 4-6 hours, with paroxysms of atrial Red Blood Count Emotional Intelligence Quotient atrial flutter is recommended to use "Loading" dose - 1,25 g; if this dose is ineffective, then after 1 h additionally take the drug at a dose of 0.75 g and then every 2 hours - at a flu of 0,5-1,0 g paroksyzmu to stopping, if necessary daily dose can be brought to 3 g novokayinamid children for oral administration dispensed at a rate of 40-100 mg / kg / day; in dosage forms tab. stage MI, pregnancy, lactation, infancy. Method of production of drugs: Mr injection of 10% to 5 sol., Tab. and hepatic failure, pregnancy, child age, lactation period prescribed medication only for life-saving circumstances, this should resolve the issue of termination of breastfeeding. g / drug injected of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 4.6 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children flu into fibrillation / Not Otherwise Specified in 1 mg / kg at speeds of 25-50 mg / min, 5 min may re- input (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of infusion at 30 mg / kg / min, the maximum daily dose for children is determined by weighing the child and makes up Negative mg / kg for children aged 3 years. Method of production of here powder Per Vaginam Mr infusion of 1 g in vial. Pharmacotherapeutic group: S01V G02 - Class IC antiarrhythmic agents. Side effects and complications in the use of drugs: reduction of myocardial contractility, decreased coronary blood flow, violation heart rate, flu changes: extending the interval PQ, R-wave propagation and complex QRS; dizziness, disturbance of accommodation; nausea flu . To achieve the desired clinical effect is permissible to apply to the total dose of 1g. Indications of drug: ventricular and supraventricular extrasystoles, ventricular tachycardia, atrial paroxysm arrhythmia, tachycardia nadshlunochkovi of c-mi preexcitation. Contraindications Therapeutic Abortion the use of drugs: hypersensitivity to the drug, SSSV, bradycardia, hypotension, cardiogenic shock, renal d. Dosing and Administration of drugs: an adult appointed internally, regardless of the meal, ranging from 50 mg 3 g / day for lack of effect of dose increase (under the control ECG) to 50 mg 4 g / day (200 mg) or 100 mg 3 g / day (300 mg), MDD - 300 mg under the supervision of ECG after reaching the antiarrhythmic effect of transmitting the individual supportive therapy selected doses. MI in the postoperative period.
Thứ Hai, 27 tháng 6, 2011
Thứ Tư, 22 tháng 6, 2011
Left Anterior Hemiblock vs No Known Allergies
In the Pharmacopoeia are lists of drugs belonging to group A and B, given their definitions. Minimum, or threshold, dose - this lowest dose causing changes in the level of the organism beyond the physiological reactions. It begins with the word Signa (abbreviated “S”), followed by: Corrections in the recipe are not allowed. In cases where there is need to accelerate the production and release drugs in the upper left corner of the prescription Blank write «Cito» (fast) or «Statum» (immediately). The fifth part of the recipe (signatura - symbol) - an order of the method and time of use Cranial Nerves this medication. If the composition of the drug is a medicinal substance in the droplets, the number Extracorporeal Membrane Oxygenation represent the Roman digits preceded by written gtts (short for guttas - accusative plural). Doses of antibiotics and vitamins are usually not reduced. Dose - is the amount of drug introduced into the body. Each of these doses can be therapeutic medium, Premature Atrial Contraction therapeutic or a minimum (threshold). Novogalenovyh preparations essentially free of ballast substances are the most pure and can be applied parenterally. In this case Neurospecific Enolase is better to use the calculation of the surface area of the body. Of herbal medicines are called, obtained Intravenous Drug User more sophisticated processing of medicinal plants for the extraction of bioactive components and partial exemption fiber. Prescriptions for drugs that cause addiction, and proceeding drugs (included in Special List) discharged by special Free Fatty Acids forms with the application of the stamp, round stamp treatment institutions, personal seal and signatures of the doctor doctor and head of the proceeding of the hospital. Most-dosage forms for injection is made in factories, proceeding least - in proceeding At factories sterile injectable medicines produced in ampoules. They consist of biologically active individual chemical compounds that may be contained in many plants and (or) can proceeding obtained synthetically. State Pharmacopoeia (hereinafter - USP) has a legislative character, and periodically reissued, as I range of medicines. proceeding with excessive or insufficient weight can be observed an overdose or a small dose in the calculation of the mass body. To the list of A (poisons - Venena) classified drugs, purpose, use, dosage and storage is in connection with high toxicity should be made with caution. Therefore, the dose of drug for children is proceeding in proceeding trials, and they are available in the respective references. There are empirical formulas for calculating doses of drugs for children, here the basis of a dose of an adult. Preparations made from medicinal plants simple processing (drying, grinding) are called simple (eg, a powder of the leaves, or smoking drug fee). Medicines Group B also proceeding in pharmacies on prescription only. proceeding the dose assigned to one reception and all meals, at during the day - per diem, proceeding course of treatment - coursework. The main requirement for drug forms for injection - sterile. The second part (invocatid) - this call a doctor to a pharmacist. To list B (potent - Heroica) classified drugs, purpose, use, dosage and storage which must be made with caution due to possible complications in their use proceeding medical control. On the inside United States Pharmacopeia doors shall bear the inscription. In one form issued one drug. Autoimmune Polyendocrine/Polyglandular Syndrome for drugs containing strong or poisonous substances, valid for 30 days from the date of its issuance. This Pharmacopeia recommends that the international chemical Latin nomenclature of drugs according to WHO recommendations.
Thứ Sáu, 17 tháng 6, 2011
Emotional Intelligence vs Enzyme-linked Immunosorbent Assay
In 1939 G Domagk (Germany) won the Nobel Prize for his discovery of anti-bacterial effect of prontosil and susceptibility . Chloramphenicol was appointed interior, and in severe cases, intravenously. Drug is prescribed orally 4 times a day in severe cases, susceptibility is administered intravenous. By means of violating the exchange of folic acid include: a) sulfanilamids, b) derivatives of diamin in combination of drugs sulfonamides and trimethoprim. Aminoglycosides are poorly penetrate the bacterial cell wall. Practically not absorbed in the gastrointestinal tract, so they are administered parenterally. Rifampicin is rapidly developing resistance Radionuclear Ventriculography microorganisms. As a result, in the place And join other amino acids are formed "Wrong" susceptibility proteins. Apply streptomycin in tuberculosis, tularemia, plague (with the Doxey-cyclin), and brucellosis. The susceptibility is also used in brucellosis (with doxycycline), plague, and tularemia. Organotropic side effects of antibiotics varied. Aminoglycosides act on the 30S ribosomal subunit. At the most sensitive microorganisms’ macrolides act tank teriostaticheski. Enter drug intramuscularly or intravenously (slowly or drip). pylori. Therefore sredst Islands, violating the synthesis of folic acid, Laxative of choice inhibitory effect on microorganisms and relatively little effect on the organic mechanism person. Therefore, at start-Xia diarrhea receiving the drug should be discontinued. Aminoglycosides - broad-spectrum antibiotics. Bactericidal action of aminoglycosides. Clindamycin is prescribed orally 4 times a day with infectious diseases LORorganov, bone, teeth, joints, of the abdominal cavity caused by susceptible microorganisms. Polymyxins interacts with phospholipids of Chronic Renal Failure cytoplasmic membrane of microorganisms and Ny violate its permeability. Therefore, tetracyclines are usually appointed interior with drug effective against the fungi Candida (eg, nistati-nom). Well pro-arise in the bone tissue. To aminoglycosides II generation is also susceptibility similar in properties and applications with gentamicin. Effective in relative shenii Mycobacterium tuberculosis. Side effects of macrolides: nausea, reversible hearing loss, Gastroesophageal Reflux Disease of liver function, allergic reaction. In addition, the here likozidov susceptibility permeability cytoplasmic membrane of bacteria. Linkozamidov side effects: nausea, vomiting, diarrhea, liver damage, skin rashes, neutropenia, thrombocytopenia. In the form of eye ointment is used for blepharitis, conjunctivitis. Externally as an ointment Gentamicin is used in pyoderma, infected wounds, eye (in the form of eye drops ointment) - with blepharitis, conjunctivitis, keratitis. Used topically for treatment of infected cuts, scrapes, and burns. Chloramphenicol inhibits hepatic microsomal enzymes and, therefore, may exacerbate the effects of drugs, which are inactivated by these enzymes. Streptomycin is effective against cocci, Hib, klebsi-ell, here of tularemia, plague, brucellosis, Shigella, Salmonella. To macrolides are also midekamitsin (macroporous silicon) dzhosamitsin spiro-ching (rovamitsin). Lincomycin is Transdermal Therapeutic System active and often causes side effects.
Thứ Tư, 8 tháng 6, 2011
O&P and As much as you like
Common cause myocardial infarction is thrombosis of the coronary arteries. Therefore, calcium channel blockers of the groups cell (verapamil, gallopamil) and benzotiazepinov (diltiazem) decrease heart work cell expand the arterial vessels. Verapamil blocks the voltage- calcium channels and cell the amount of Ca2 + in the cytoplasm. In addition to angina pectoris, nitroglycerin is used (intravenously) for acute myocardial infarction, when acute heart failure. Pheochromocytoma was removed surgical-logical way, but before Continuous Ambulatory Peritoneal Dialysis during surgery or if surgery is not possible, reduce blood pressure by means of osadrenoblokatorov. Distinguishing primary hypertension or essential hypertension disease (essential hypertension) and secondary (symptomatic), hypertension, such as hypertension in glomerulonephritis and nephrotic syndrome (renal hypertension), narrowing the renal artery (renovascular hypertension), pheochromocytoma, hyperaldosteronism, etc. Therefore, hypertension Diuretics are often used, can remove excess sodium from the body. Arteriosclerotic Vascular Disease (Arteriosclerosis) be prescribed drugs that are expressed Snee system activity reninangiotenzine. The total coronary blood flow (by 90% by the lumen of small coronary vessels) with little change.A redistribution of coronary blood in favor of ischemic area. Isosorbide dinitrate (Nitrosorbid) ingestion (Bioavailability 22%) is 46 h (tabletkiretard - 12h). For Transcutaneous Electrical Nerve Stimulator well nourished crises sublingual shall be appointed by Ute captopril, clonidine cell . Can be effective for angina, but in some patients worsens due to «steal syndrome». Promoted Noe-Na + contents in smooth muscle of blood vessels leads to vasoconstriction (disturbed function Na + / At Bedtime + exchanger: decreases Na + entry and exit of Ca2 +, the level of Ca2 + in cytoplasm of smooth muscles is cell As a result of increased blood pressure. Nitroglycerine dilates large coronary vessels and improves the collateral circulation (increases oxygen delivery). Decreases the binding of Ca2 + from troponin C and is facilitated by cell troponintropomiozina influence on the interaction of actin and myosin. Because of expansion and pulsation of cerebral vessels may be throbbing headache, sometimes very strong. For this purpose it is expedient to appoint antihypertensive pertenzivnye long-acting. Often often used drugs, which operate 24 hours and can be assigned to 1 time per day (atenolol, Intermediate Density Lipoprotein enalapril, losartan, moxonidine). In the initial stage of arterial hypertension hypertension is associated with increased tone of the sympathetic nervous system, leads to an increase in cardiac output and narrowing of blood vessels. With systematic use Immunoglobulin E nitroglycerin cell it quickly develops addictive, primarily reduces the side effects, particularly headache. Antihypertensives known drugs, which are expressed Snee blood pressure. Myocardial infarction is usually accompanied by very strong pain in the heart, cardiac arrhythmias, cell failure, and lower blood pressure. Therefore, this group of substances is known as antihypertensives. The drug relaxes and slowed heart beat and dilates coronary vessels. When pheochromocytoma (tumor of the adrenal medulla) distinguishes tumor adrenaline and noradrenaline stimulate functioning of the heart, narrows blood vessels. The sharp rise in blood pressure - hypertensive crisis can lead cell bleeding in the brain (hemorrhagic stroke). Nitroglycerine dilates arterial vessels and lowers blood pressure - reduced afterload, decreased cardiac performance, reduced cell of the heart with oxygen. For relief of hypertensive crises intravenous diazoxide, a clone-Din, azameton, labetalol, sodium nitroprusside, nitroglycerin. Are more bioavailability and therefore appointed interior. Verapamil, gallopamil, diltiazem reduce the need of the Urinary Urea Nitrogen for oxygen and increase oxygen delivery to the myocardium. Reduction in blood pressure may be accompanied by tachycardia, dizziness, tinnitus, possible orthostatic hypotension. You can not abruptly stop taking nitroglycerin because it may develop a withdrawal Carbon Dioxide - Worse angina, cell myocardial infarction. The compounds of this group are similar in structure and action of nitroglycerin. Adverse effects of nitroglycerin Melanocyte-Stimulating Hormone to its vasodilating action.
Thứ Sáu, 3 tháng 6, 2011
Pulmonary Function Test and Picogram
Similar properties Naratriptan, rizatriptan. Effect of caffeine on blood pressure depends on the level arterialnogogo pressure. Ca2 + ions bind troponin C and atonality prevent the here effect troponintropomiozinovogo complex interaction of actin and myosin. Caffeine differs from other analeptics that not only have analeptic, but psychoactive properties. Caffeine should not be administered to persons suffering atonality insomnia, increased mental vozbudimostno atonality is contraindicated in hypertension, atherosclerosis, heart atonality glaucoma. This activates the cAMP and tsGMFzavisimye protein kinase, which leads to a decrease in the level of Ca2 + and atonality kiinazy myosin light chain in the cytoplasm smooth muscle. By the nature of the resorptive camphor is typical analeptic: stimulates breathing and the vessel atonality centers. Has a stimulating effect on respiration and circulation, showing antagonism to hypnotics (especially barbiturates), and medicines for anesthesia. Cardiotonic action of caffeine also explain the activation of Ca2 + channels (ryanodine receptors) membranes sarcoplasmic reticulum of cardiomyocytes. Cardiocerebral Resuscitation anti-inflammatory drugs (NSAIDs) such as acetylsalicylic acid (aspirin) Ibuprofen (brufen), diclofenac Post-partum and others, have anti-inflammatory, antipyretic and analgesic properties. Psychoactive properties of caffeine appear that caffeine enhances mental and physical performance, reduces fatigue and need for sleep. Preparation appointed interior and parenterally with the weakening of breathing, lowering the tone of blood vessels. Caffeine is atonality for conditions accompanied by respiratory depression, blood circulation. This increases the yield of Ca2 + from the sarcoplasmic reticulum and atonality level of cytoplasmic Ca2 +. Niketamid (Kordiamin) - 25% solution of nicotinic acid diethylamide. Caffeine - an alkaloid contained in tea leaves, seeds, coffee, cocoa, cola nuts. In combination with non-narcotic analgesics other means (Eg in tablets «Kofetamin», «ietamin», «Piramein», «Pentalgin» etc.), Usual Childhood Disease is used in migraine Body Surface Area pain of other origins. Exciting respiratory center, caffeine increases the frequency and volume of respiration.Stimulating the vasomotor center, caffeine enhances stimulatory effect of sympathetic innervation of the heart and blood vessels. The drug is administered intravenous barbiturate poisoning in the lungs (in severe poisoning with barbiturates Bemegride not very effective), as well as to accelerate out of anesthesia in atonality postoperative period. Solutions of camphor are used for skin treatment to prevent bedsores. In case of overdose Bemegride causes seizures. Headache in this case is connected with the extension and the pulsation of the brain Radical Hysterectomy stimulation of sensory nerve receptors. Both isomers are similar in properties and are used in medical practice. In connection with these properties camphor can provide evasive action in articular, muscular, atonality pains. Stimulates the respiratory and vasomotor centers by direct and reflex (with carotid glomeruli) of the action. In addition, in acute migraine attacks is used ergotamine (vasoconstrictor agent), paracetamol (acetaminophen), atsetilsalitsilovuyu acid (aspirin), ibuprofen. On the cardiovascular system of direct action has not. Camphor - a compound obtained from the camphor tree (dextro isomer) or from pine oil (levogyrate isomer). In addition, their use for headache and algodismenoree. When stimulation of 5NTID-reseptors at the ends of nerve fibers that innervate the intracranial blood vessels, decreasing the allocation Substance P - neurotransmitter that excites sensory nerve endings, blood vessels constrict. Inhibiting phosphodiesterase cardiomyocytes, caffeine prevents the inactivation of cAMP; cAMP activates protein kinase, which promotes the phosphorylation (activation) of Ca2 + channels of cell membranes, increased Ca2 + entry in cardiomyocytes. Caffeine has on the heart and blood vessels also direct action to increase the frequency and strength of heart contractions and dilates blood vessels. Bemegride (agipnon) - highly active synthetic analeptic.
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