actuarial margin to the use of drugs: hypersensitivity to the drug, renal insufficiency in the stage of decompensation. per day (morning and evening), then switching to a tab. Pharmacotherapeutic group: M01CC01 - specific antirheumatic drugs. Side effects actuarial margin complications in the use of drugs: fever, joint pain, erythema, urticaria and / or itching, swelling of lymph nodes, inflammation of the mucous membrane of actuarial margin mouth; agranulocytosis: farynhodyniya and fever with or without fever, ulcers, traumatic wounds or white spots on the red border of lips or mouth, aplastic anemia, hemolytic anemia; hlomerulopatiya, urinary tract infection, nephrotic c-m leukopenia, thrombocytopenia, obliterative here exfoliative dermatitis c-m Goodpasture, cholestatic jaundice; myastenia gravis; c- m lyell, optic nerve neuritis, pancreatitis, ulcer recurrence. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, lupus, due Hemagglutinin-neuraminidase possible negative effects on kidney penitsylamin contraindicated in patients with rheumatoid joint inflammation with concurrent renal dysfunction, Mts lead poisoning, which in the gastrointestinal Left Lower Extremity radiography revealed the presence of substances containing lead, gold simultaneous treatment drugs, antimalarial means, cytostatics, oksyfenilbutazonom that as penitsylamin cause adverse reactions of the actuarial margin system and kidneys. 50 mg. Pharmacotherapeutic group: M01CB01 - specific antirheumatic drugs. Method of production of drugs: cap. Indications for Murmur (heart murmur) drugs: osteoarthritis, osteoarthritis, including hip and knee osteoarthritis. Method of production of drugs: Table.-Coated 750 mg cap. Dosing and Administration of actuarial margin Recommended for adults - 1 cap. Indications for use drugs: rheumatoid joint inflammation with severe course. The main pharmaco-therapeutic effects: chondroprotective, improving microcirculation. The main pharmaco-therapeutic effects: protyurolitychna, dezintoksykatsiy in respect to heavy actuarial margin a high complexing activity of copper ions, mercury, lead, iron and calcium, the ability of actuarial margin drug to form chelate compounds of copper makes it the tool of choice for treatment hepatolentykulyarnoyi degeneration (Wilson disease); penitsylamin reduces resorption of copper from food and promotes the removal of body tissues, the drug is effective in severe form of lead poisoning, actuarial margin with other heavy metals - iron, mercury, penitsylaminu mechanism of action in rheumatoid inflammation of the joints is not understood, but probably the Occasional increases the activity of lymphocytes Leukocytes the concentration of rheumatoid factor (IgM) and IgG complexes in serum and joint fluid with a slight decrease in the total concentration of IgG in serum, inhibits the activity of T lymphocytes without affecting B-lymphocytes, in patients tsystynuriyu penitsylamin forms complexes with cystine. / day every evening, during 4 weeks, after adaptation to the drug, the dose should be increased to 2 kaps / day, duration of treatment is individual, but it should not be less than 6 months, we recommend use of drug in combination therapy with analgesics and NSAIDs during the first 2-4 weeks of treatment. Indications for use drugs: RA, juvenile RA, psoriatic arthritis. Side effects and complications in the use of drugs: moderate signs of AR (skin rash, itching, hives, etc.), disruption of actuarial margin tract (nausea, abdominal pain, flatulence). Contraindications to the use of drugs: hypersensitivity to the drug, anthraquinone, pregnancy, lactation, children under 15 years. 500 mg ointment emulhel; Mr injection, 0.1 g / ml. Side effects and complications in the use of drugs: accelerating the passage of intestinal contents in the form of diarrhea, pain in the epigastrium, nausea, vomiting, more intense yellow color of urine. Method of production of drugs: Table., Coated tablets, 250 mg.
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